Amidotrizoic acid/diatrizoic acid, iopromide, iogamidol and iomeprole are the most common substances and can be found in the highest concentrations in the aquatic environment. The tendency towards increasing consumption, solubility, stability and polarity leads us to expect an increase in the freight rates in water.
In contrast to therapeutic drugs, X-ray contrast media are developed as biologically inactive substances. The ecotoxicity of RKM has so far been assessed as relatively low. Due to the high and increasing consumption, their solubility, polarity and stability, however, they are now found in many surface waters and partly also in drinking water. Precautionary action is therefore called for.
Various preventive and additive measures are available to prevent the emission of drugs into the environment. Numerous research and pilot projects have been carried out in recent years to eliminate trace substances from municipal wastewater. The results showed that both the application of ozone and the use of activated carbon are available as practical methods for the targeted elimination of micropollutants (4th purification stage). With both methods, a broad spectrum of micropollutants can be removed from the wastewater on a comparatively high scale. They are also easy to integrate into the existing purification process of a wastewater treatment plant. For RCMs, however, both processes have low elimination rates, so that other approaches to emission reduction must be investigated. Since RKM is rarely used in individual patients and is almost completely excreted by them within a short time after application, separate collection of the collected urine can be used to reduce RKM levels in municipal wastewater.
Previous and ongoing studies focus on measures for recording RKM in clinics. The recording of RKM in the context of doctors' practices and outpatients has not yet been investigated.
The acceptance and use of the systems by staff and patients plays a decisive role in the successful reduction of RKMs through acquisition systems. In MindER acceptance studies are therefore an essential part of the work. In addition, the effectiveness of decentralized collection systems for urinary excreted RKM will be investigated and questions on cost-effectiveness will be answered.